Entomopathogenic viruses update July 2016

In the second BIOCOMES year in addition to the production of LdMNPV in static systems like T-flasks, the Lymantria dispar cell line was also successfully established in dynamic systems like TubeSpin® bioreactors.

The optimisation of the process parameters for the virus production in dynamic systems was done with the micro bioreactor system BioLector® applying statistical experimental designs. The nucleocapsids of the produced LdMNPV occlusion bodies are analysed by electron microscopy in order to detect any structural changes during serial passage in the cell culture.

See our earlier update on Entomopathogenic viruses (March 2015)

Read more about our activities on Entomopathogenic viruses

Author

Markus Züger
Markus Züger
Production of viruses
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