Entomopathogenic viruses

Entomopathogenic viruses can infect and kill pest insects. In nature there are entomopathogenic fungi, nematodes, bacteria and viruses everywhere. They contribute to the natural regulation of many populations of pest insects.

In vitro production

The entomopathogenic virus LdMNPV for example is highly effective against gypsy moth, Lymantria dispar. This pest causes losses in forestry in different climatic zones.

So far a LdMNPV production is possible in vivo using the pest insect as host to meet the market requirements. BIOCOMES will focus on the development of the in vitro production of this LdMNPV virus to allow a significant further up-scaling of the production. The in vitro production of the LdMNPV agent will be developed in cell cultures to replace in vivo production depending on insect rearing. The BIOCOMES biological control agent that will be developed against gypsy moth will include this pilot technology.

Markus Züger
Markus Züger
Production of viruses

Current stage of the Biological Control Agent



Want to know more about this project? Feel free to contact us!

Contact us

Subscribe to our newsletter

The BIOCOMES project has come to an end. The last newsletter has been sent.


Four years of public-private cooperation results in successful development of new biological control products

The EU project BIOCOMES started at the end of 2013 and aimed at the development of new biological control products. Now, at the end of the project, two new biological control products are...

Read more

“The end of BIOCOMES marks a good start”

“’The results of four years of BIOCOMES have been better than expected,” says project coordinator Jürgen Köhl of Wageningen University and Research. “This partnership between 14...

Read more


No publications found

View all publications

Share this